Is LADASTEN [BROMANTANE] the “Lada” of Russian drugs?

Jonathan Roseland
6 min readMar 24, 2019

Bromantane was developed in the 1970s at the Research Institute of Pharmacology in Russia, it was the first pharmaceutical of its kind that exhibited simultaneously both mild psychostimulating and anxiolytic effects.

LADASTEN (as it’s referred to as a pharmaceutical) meets the profile of the kind of drug that Biohackers like to use as a smart drug; the polarity of psychostimulating and anxiolytic effects imbue an ideal mindset of relaxed arousal.

This article is mostly going to focus on decoding what the human studies are saying about Bromantane and how this squares up with the anecdotal experiences of Biohackers online.

Scientific Research

It’s been studied worldwide and has been the subject of about 20 articles of human research that can be found on Pubmed, including 9 clinical trials — Semax in comparison has 30 articles of human research. We suggest getting familiar with this research…

The pilot clinical trial of Ladasten was published in 2006

Ladasten exhibits a unique combination of therapeutically significant stimulant and anxiolytic effects, which is unusual of psychostimulants. At the same time, the results of ladasten action upon single administration on the dynamics of psychopatological disorders and psychological self-test indexes show that the psychostimulant action is predominating.

The most significant trial was published in 2010; it was carried out in 28 different clinical centers and included data from over 700 Russians suffering from psychoautonomic syndrome and asthenic disorders.

We determined clinical efficacy of ladasten in regard to anxiety-depressive spectrum disorders, autonomic dystonia, sleep disorders. Ladasten therapy led to the significant increase of quality of life, which was seen not only after the end of therapy, but after the withdrawal of the drug…
In conclusion, the efficacy of ladasten was shown in its antiasthenic, anxyolytic, autonomic nervous system stabilizing properties, the normalization of sleep-awake cycle and the increase of quality of life.

The study notes an onset of beneficial effects on day three of dosing and that the helpful effects lingered for some time after going off the drug.

Vs Neurasthenia

A 2012 Russian placebo-controlled study established it as an effective treatment of neurasthenia, which is a generalized condition in which one suffers from fatigue, headache, and general moodiness

The self-assessment of the effect of single test doses of ladasten and placebo was independent of the individual differences of EEG alpha rhythm organization and personal traits with respect to tolerability, wish to continue the treatment, activating and calming effects. In long-term treatment, higher subjective estimations of the ladasten and placebo effect appeared in patients with reduced EEG alpha rhythm…

Physical Performance Enhancer

Bromantane was used by seven Russian athletes, including two medalists, during the 1996 Atlanta Olympic Games, following which the compound was added to the banned list as a stimulant and a masking agent. A story in The Independent (back in 1996 when it was presumably more independent) described…

Bromantan, which combines the properties of steroid, stimulant and masking agent — effectively the Grand Slam in doping terms — was developed by the Russian national institutes for pharmacology, and has allegedly been used by the Russian army and by cosmonauts. It is also serving as “rocket fuel” for Russian and east European competitors at the Games.

Libido Enhancer

A 2004 study and at least one very randy Biohacker found it had a positive effect on sexual appetite.

Sources in the USA offers COA-verified, pure Bromantane as a solution and powdered, the most economical form.

Clinical Indications

According to the manufacturer and independent clinical studies, Ladasten may help to reduce anxiety and delay the onset of physical and mental fatigue. Other benefits may include…

  • Reduce Fatigue / Boost Energy
  • Increase Physical Stamina
  • Relieve Anxiety / Improve Sleep
  • Elevates & Stabilizes Mood
  • Boost Memory, Focus & Concentration
  • Non-Toxic & Non Habit Forming

Ladasten® can be used by those who have the following symptoms:

  • Asthenic disorders of different types, e.g. somatic symptoms disorders and after-effects of infections
  • Neurasthenia (exhaustion of the central nervous system’s energy reserves).
    One pack of Ladasten ® contains 25 or 50 pills, each with 50 mg of the active ingredient; one pack is sufficient for approximately 5–10 days of administration.

Side Effects

From the study of 700 Russian patients, Adverse effects were observed only in 3% of patients, the therapy was discontinued in 0.8%. No serious adverse effects were found.


This is a smart drug that I’ve heard described in quite grandiose terms from veteran Biohackers with a little higher risk tolerance. From an experienced Nootropics user in my inner circle…

I have a pretty extensive history with nootropics but going into bromantane I was not expecting anything like this. I have several severe mental problems and I do not use the word severe lightly.

I noticed within a few hours of my first dose that I was going to like it and for some reason knew it would help me and I have never got that feeling ever from a medication or chemical. The fact that it lasted almost all day made it better.

I went with the pegelated bromantane and loved it and noticed energy within 2 hours but not the energy that you get from stimulants but you are up cleaning and doing and getting things done and that’s a significant difference that a lot of people look for in something when looking for motivation. Bromantane genuinely motivates you. Also it seemed to live up to its “bro” name and kinda made me act a bit more alpha… while on it. Some people don’t get this or any positive benefit from the drug but wow my brain was waiting for this. I just had no idea. If they ever… create[d] a drug that turned you into a type-b person into a type-a person, this is it!

I feel confident and comfortable and in control but not high. Also very important because being normal is just that. Not being high. Not feeling in control because of euphoria but being in control because it just puts you straight into clutch mode.

We have a lot to learn from bromantane. I know I did and it’s changed my life.

It did make me require less sleep. And I did take my dog out in the snow in my boxers several times and noticed it’s ability to make me just not be bothered by the cold. I’m sure my neighbors liked that

It seemed to cause a sexual appetite increase as well. In fact this became an issue. I’d dose and 2 hours later I’d really be down to have some intimate time with my girl who wasn’t always down which turned into a really good thing. I began to work out.
In fact by day 3 on bromantane I was working out almost 2 times a day.

I took creatine with it and amino acids especially the ones that induce growth l-arginine L-ornathine l-lysine since bromantane actually modulates your DNA at its very base my increasing the amounts of the four basic amino acids in your DNA.

I can see why people would be into it for a study drug. My brain worked much faster as it healed it and I was basically smarter while I took it an more importantly was in “a game” mode when I took it which is exactly what I needed. I even wondered if it or something like it is the NZT mane say is real. Bromantane is worth more than a try in my honest opinion.

Originally published on I’m not a doctor, medical professional, or trained therapist. I’m a researcher and pragmatic biohacking practitioner exercising free speech to share evidence as I find it. I make no claims. Please practice skepticism and rational critical thinking. You should consult a professional about any serious decisions that you might make about your health. Affiliate links in this article support Limitless Mindset — spend over $100 and you’ll be eligible to join the Limitless Mindset Secret Society.



Jonathan Roseland

Adventuring philosopher, Pompous pontificator, Writer, K-Selected Biohacker, Tantric husband, Raconteur & Smart Drug Dealer 🇺🇸