This video made me the MOST HATED man in the Kratom community - they did not take my reasoned criticism well! But there is some reason for optimism, in 2020 we finally got A Randomized, Placebo-Controlled, Double-Blind Study on Kratom and Pain Tolerance - a collaboration between Yale School of Medicine and a Malaysian university. The study involved just a 1-day inpatient stay and 26 male subjects, but it's a good start.

Especially when it comes to Kratom, as I say in the video, where ever the financial incentives create moral hazard, you need to look for evidence of quality.